在中国古代，选择皇帝的正室——皇后——时，实施了一套极为严格的婚前健康检查制度。历史记载中，东汉桓帝想要立大将军梁商的女儿梁女莹为皇后。在这过程中，一位名叫吴婀的女官被派遣到梁府进行检查。

首先，吴婀观察了梁女莹的走路姿势，然后要求她进入闺房接受更细致的身体检查。出身于豪门家庭的梁女莹对此感到强烈抗拒，但面对吴婀展示的一把“尚方宝剑”，表示这是皇上的圣旨和选后规矩，她才勉强同意接受检查。

Wu Bai进行了一系列详尽的手术体检：她检查了是否有肿瘤或包块、嗅探是否有狐臭或鼻炎气味；然后she examined the shape and depth of her navel, the width of her shoulders, waistline, arm elasticity, skin color and length of legs, hand size and fingers as well as foot arches and toe colors. Finally she conducted a gynecological examination and asked about any medical history.

Afterwards, Wu Bai re-examined her five senses including hair density and color; checked her ears, teeth, nose bridge, eyes brows. At last she asked Yang Fei to shout "Long live" three times to test her vocal cords' function.

In June 147 AD (the first year of Emperor Huan's Jianhe period), Yang Fei officially entered the palace; in August she was formally crowned Empress. This might be one of the earliest recorded examples in Chinese history where an empress underwent pre-marital health check-ups.